250mg/ml - 10ml/vial
Anabolic/Androgenic Ratio: 100/100
Risk of estrogenlevels/estrogen-mediated effects: Yes, moderate
Risk of cardiovascular issueswith use: Yes, moderate
Risk of hepatic strain withuse: No
Testosterone Enanthate: The Chemistry And Pharmacology
Testosterone Enanthate 250 is a synthetically generated form of the namesake hormone that almost anyone can find, being produced endogenously in their bodies. During the 20th century, scientists helped synthesize the hormone, in order to help treat medical ailments related to testosterone deficiency, or secondary illnesses like muscle wastage.
The chemical does differ slightly with the addition of a chemical delivery agent Enanthate, also known as an ester. As its terminology might imply, this attachment determines how the active testosterone is delivered into the body once it’s injected. Usually, normal testosterone on its own would only exert its effect on the body over a period of a few hours.
However, with the attached delivery agent, this time extends to roughly a week, with a half-life of 4 to 5 days. This means it can carry out is effects over this period.
Namely, these effects include binding to select receptors in the body, known as androgen receptors, at specific cells like muscle fibers and bone cells. When bound, it causes a change in the signaling within these cells which, when consistently carried out over time, exert global effects around the body like increased lean tissue and bone density, as well as a boost in red blood cell production, all of which testosterone use is associated with, in both medical and athletic circles.
During this process, it also interacts with other enzymes like aromatase, which partially converts some of it to estrogen, and 5-alpha-reductase, which helps partially convert it to Dihydrotestosterone. All of these other processes can cause additional, potentially undesirable effects, which are discussed below, after we look at how Testosterone Enanthate is commonly used.
As mentioned in the previous section, testosterone was originally used for medical and research purposes. However, many athletes starting incorporating its use unofficially when they saw the benefits it could have on lean mass growth and associated performance in strength and power capabilities.
This type of testosterone is relatively moderate in its rate of release. So, it’s commonly used in periods where either gradual and efficient gains in lean mass and power, or, in tandem with other anabolics, in periods where relatively rapid but inefficient gains in mass and strength are the goal. Either way, these programs can last from 12 weeks all the way up to a year. It should be noted that, depending on the objective of the program, different doses as well as combinations, will be used. This is why we’ll review these below.
Because of the informal nature of anabolic use for athletic or aesthetic goals, there wouldn’t be an overarching guideline for dosing for Cush purposes. However, there are commonly reported doses in both research and in anecdotal reports. These are dynamic, and can change based on goals, as mentioned above, the prior experience of the user with such anabolics, as more seasoned users are more accustomed to their effects and will need higher doses, and gender, as females are more sensitive to the effects of anabolic agents.
Commonly reported amounts for men are between 250 to 500 milligrams each week for beginners, and between 1000 to 2000 milligrams each week for more advanced users, with females recommended to stay away from its use, due to some negative side effects which will be reviewed in detail below.
As alluded in the previous sections, the way in which exogenous testosterone is processed in the body gives way to a number of potential unwanted effects with its use, that should be considered in tandem with its benefits by anyone looking to purchase it. Such effects may involve:
- Cardiovascular related issues: these include problems like a buildup of unhealthy LDL cholesterol levels, increased arterial stiffness and enlarged heart size.
- Estrogen-mediated issues: these include problems like a buildup in fluid in the body, which may increase bloating, and increased fat accumulation, as well as the risk of excessive breast tissue development in men, known as gynecomastia.
- Androgenic issues: these can involve skin problems like bouts of oily skin and acne, balding at a faster rate in those genetically predisposed, and the development of male traits in women, known as virilization, which can become permanent.
- Testosterone suppression: this would primarily affect men and involves the reduction or cessation of endogenous production of the hormone due to excess exogenous amounts in the system, which persists even after these exogenous amounts are depleted.
While some of the above-mentioned side effects
are manageable with ancillary agents like SERMs, Aromatase Inhibitors, and
5-alpha-reductase Inhibitors, the ultimate form of management is to monitor and
manage dose or to stop using it if undesirable effects are unbearable. Use
should also be carried out only under medical supervision, to ensure safety and
efficient use. The effect on endogenous testosterone production will also
necessitate a good Post Cycle Therapy program to ensure rapid recovery of
endogenous manufacturing, while limiting unwanted deficiency-related events at the
|Package||1 vial (10 ml/vial)|
|Substance||Testosterone Enanthate 250 mg/ml|
|Common name||Testosterone Enanthate|